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Science & Technology
Parkinson's Isn't Just Bad Luck. Scientists Reveal It's Largely Preventable‐and the Culprit Is All Around Us
2025-08-21
[Oprah Daily] When my grandfather was diagnosed with Parkinson’s disease in 2014, I assumed it was pure bad luck—perhaps from some secret misprint wired deep in his genetic code, or something that "just happened" to certain people as they aged. Parkinson’s slowly deteriorates the brain’s basal ganglia (which are in charge of movement control). It caused my grandfather, who has since passed away, to suffer from seemingly uncontrollable tremors in his hands, as well as stiffness, trouble walking, and rapid weight loss. "This is hell," he told me once.

But as I’ve learned from reading The Parkinson’s Plan, a new book from neurologists and researchers Ray Dorsey, MD, and Michael Okun, MD, the disease that affects 1.1 million Americans is not, as I’d assumed, just an unlucky break. Drs. Dorsey and Okun draw on decades of research to argue that Parkinson’s is preventable, not inevitable—and that it is driven in large part by modern pollution and chemical exposure. They propose a comprehensive plan, which calls for $3 billion of federal funding to tackle the environmental causes, bolster research efforts, increase access to care, and invest in new treatments. Their mission is to eradicate Parkinson’s once and for all.

"We wrote this book to prevent future generations from ever getting this disease," Dr. Dorsey tells me. "We wrote this book to help slow the rate of progression for those who already have the disease, and we wrote this book to come up with better ways to treat the disease." We spoke to Drs. Dorsey and Okun about what they’ve learned over their careers studying and treating Parkinson’s disease and what we all can do to reduce our risk.
Posted by:Besoeker

#9  That’s very good to know, Remoteman. Thank you, and your sweetheart, too.
Posted by: trailing wife   2025-08-21 22:15  

#8  My sweetheart is one of the world’s leading Parkinson’s researchers. We have two companies going after separate genetic forms of the disease. One is a gene replacement of the gene named Parkin. If you are born without the two alleles (one from mom, one from dad) of this gene you will get early onset Parkinson’s in your late teens or early twenties. If you get only one allele you will also get Parkinson’s early, just later in life. We are on the path of FDA approval and hope to start human trials in a couple years. Prolonged pesticide exposure causes similar symptoms and she believes (supported by human cell testing) that the introduction of the Parkin gene to these patients should positively impact the disease progression. Lots of work being done on the genetic forms of the disease which should help set a pathway towards dealing with the non-genetic forms.
Posted by: Remoteman   2025-08-21 14:33  

#7  James Parkinson, who named the disease, did his work in the early 1800s. The condition had been recognized for centuries before that (going back to 10 century BCE Egypt).

The so called 'modern pollution and chemical exposure' hypothesis is somewhat inconsistent with this.
Posted by: Lord Garth   2025-08-21 13:55  

#6  Oprah, huh?
Posted by: Abu Uluque   2025-08-21 12:44  

#5  No supper for you DooDauMan.
Posted by: Besoeker   2025-08-21 12:19  

#4  
Posted by: DooDahMan   2025-08-21 11:42  

#3  Our body is a mosaic of fungi. Some scientists think they could be influencing our brain
Posted by: Skidmark   2025-08-21 09:47  

#2  ...which calls for $3 billion of federal funding

Nuff said
Posted by: Procopius2k   2025-08-21 07:55  

#1  $3B seems like a good value. It’s less than supporting Stacey Abrams cost us.
Posted by: Super Hose   2025-08-21 06:28  

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